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To enhance your diagnostic reasoning skills, follow these steps:
- Review the Information: Carefully read through the content in each section of the case scenario.
- Consider the Question: Reflect on the Diagnostic Reasoning Question presented. Take your time to think about your answer.
- Compare Your Answer: Attempt to answer the question before viewing our suggested answer. When ready, click “View Suggested Answer” to compare it with your own.
Repeat these steps for each section of the case scenario. Please note that the suggested answers are only indicative and not exhaustive. They serve as guidelines and should not be considered complete answers.
Patient’s History
In the sections below, you will find case history information designed to guide you through a systematic approach to performing a focused and relevant case history. This process will help you narrow down the potential causes of the patient’s complaint. As you go through the material, we encourage you to answer the questions provided to test and enhance your diagnostic reasoning skills.
Who is the patient and where is the pain?
When was the onset and what caused the onset?
Natalie, a 32-year-old teacher, presents with a two-week history of right-sided facial pain. She identifies the area in front of her right ear as the primary site of discomfort. The pain began within 24 hours after undergoing a prolonged dental procedure to repair a cracked tooth. Natalie has since revisited her dentist, who advised the use of painkillers and suggested that the pain should resolve with time.

Diagnostic Reasoning Question 1
What differential diagnoses would you consider for Natalie?
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Pain in the preauricular region can indicate several conditions, including:
- Temporomandibular joint dysfunction
- Myofascial pain syndromes (e.g., involving the medial and lateral pterygoids, masseter, and sternocleidomastoid muscles)
- Upper cervical facet joint dysfunction
- Dental conditions (e.g., caries, abscess, malocclusion)
- Otitis media and otitis externa
- Trigeminal neuralgia
- Post-herpetic neuralgia
- Giant cell arteritis (temporal arteritis)
- Parotitis
- Mandibular fracture or dislocation
- Cancer of the jaw, head, or neck
Diagnostic Reasoning Question 2
Based on the patient’s history, how would you differentiate between trigeminal neuralgia and temporomandibular joint (TMJ) dysfunction?
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- Trigeminal Neuralgia – Trigeminal neuralgia is characterized by sudden, severe, stabbing, or electric shock-like pain that typically lasts from a few seconds to a few minutes. The pain is usually localized to specific branches of the trigeminal nerve and often affects one side of the face. Light touch, movement, or even routine activities like chewing or speaking can trigger these intense pain episodes.
. - TMJ Dysfunction –Temporomandibular joint (TMJ) dysfunction often presents with pain localized to the temporomandibular joint, which may radiate to the jaw, temples, neck, or surrounding areas. The pain is frequently aggravated by activities such as chewing, clenching the jaw, or other jaw movements. Patients may also experience clicking or popping sounds in the jaw joint, restricted jaw movement, muscle stiffness or tenderness in the jaw or face, and sometimes, headaches.
What are the pain characteristics?
What are the aggravating and relieving factors?
What has been the course of the pain?
Natalie describes the pain as a constant, dull ache with sharp exacerbations triggered by jaw movements, particularly during chewing or yawning. She rates the dull ache at 3 out of 10 in intensity, while the sharp exacerbations reach 9 out of 10. Applying an ice pack directly over the painful area provides temporary relief. Although she initially took painkillers as advised by her dentist, which also offered brief relief, she has since stopped taking them and seeks your assistance to address the underlying issue. The intensity of her pain has remained unchanged since it began.
Diagnostic Reasoning Question 1
What are the potential causes or underlying conditions that could result in a patient experiencing a constant dull ache in the jaw, with sharp exacerbations triggered by movements such as chewing or yawning?
ViewHide Suggested Answer
Her description of pain aggravated by jaw movement strongly suggests involvement of the temporomandibular joint (TMJ), the muscles of mastication, or a dental issue. However, it could also indicate the possibility of an external or middle ear infection.
Diagnostic Reasoning Question 2
How does the temporary relief from ice packs and painkillers contribute to our understanding of the underlying condition?
ViewHide Suggested Answer
Pain relief from applying an ice pack may suggest an underlying inflammatory process, though it could also reflect an analgesic effect similar to that provided by painkillers.
Are there any associated symptoms?
Upon further questioning, Natalie reveals that the sharp exacerbations of pain are accompanied by a clicking sensation in her right jaw when chewing or yawning. The dull ache in her jaw sometimes radiates to the right side of her head, particularly after a full day of teaching. Additionally, she reports a mild earache on the right side and suspects that her hearing in that ear may be slightly diminished.
Diagnostic Reasoning Question 1
How does jaw clicking accompanied by pain contribute to the diagnostic process?
ViewHide Suggested Answer
An occasional, painless jaw click is common in the general population. However, dysfunction of the temporomandibular joint (TMJ), such as disc displacement or joint degeneration, can lead to sharp pain exacerbations and clicking sensations during jaw movements. Additionally, clicking accompanied by pain when chewing may indicate changes in bite alignment due to dental issues.
Diagnostic Reasoning Question 2
How does the spread of jaw pain to the side of the head, along with associated symptoms like mild earache and diminished hearing, inform the diagnostic process?
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A dull ache in the jaw that spreads to the side of the head, especially after prolonged jaw movement (such as a day of talking), is often consistent with referred pain from TMJ dysfunction. TMJ dysfunction can cause pain to radiate to nearby areas, including the head and neck. However, similar referral patterns can also arise from myofascial pain syndrome, dental issues, or ear infections. Perceived hearing loss might suggest an ear infection, though it has also been reported in cases of TMJ dysfunction.
Is there any past history that may be relevant to the current complaint?
Natalie has no past history of jaw pain.
Diagnostic Reasoning Question
How does the absence of a previous history of jaw pain inform the diagnostic process?
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Her lack of a previous history of jaw pain suggests that the current issue may be acute or the result of a recent event rather than a chronic or recurring condition.
Are there any red flags?
The following questions are asked to identify any “red flags” that could suggest serious pathology. Even if the patient has previously mentioned related information during the case history, it is recommended to revisit these questions to ensure a comprehensive evaluation.
- Do your symptoms disappear even for a short time? “Yes. I am not aware of the pain when I first wake up in the morning.”
- Does the pain wake you up at night? “No.”
- Are you experiencing any dizziness or loss of balance? “No.”
- Have you recently had any fever, chills, or night sweats? “No.”
- Have you recently had an infection or other illness? “No.”
- Have you had any unexplained weight loss recently? “No.”
- Do you have a history of cancer, inflammatory arthritis, or fracture arising from minor trauma? “No.”
Diagnostic Reasoning Question
Do any of the patient’s answers raise a red flag?
ViewHide Suggested Answer
None of the patient’s responses raise a red flag.
Differential Diagnosis
Diagnostic Reasoning Question
Based on the available history, how would you prioritize the list of differential diagnoses?
ViewHide Suggested Answer
- Temporomandibular joint dysfunction
- Myofascial pain syndromes (e.g., involving the medial and lateral pterygoids, masseter, and sternocleidomastoid muscles
- Dental malocclusion
- Otitis media and otitis externa
- Upper cervical facet joint dysfunction
Reflection Point
Pause and consider whether the key elements of a thorough and relevant patient history have been addressed. Are there any additional questions you would have asked? If so, what are they, and why would they be important?
Before reviewing the physical examination findings below, take a moment to reflect on which physical examination procedures you would perform to accurately assess this patient.
Physical Examination
In the sections below, you will find physical examination findings for this patient. The material outlines a systematic approach to conducting a focused and relevant physical examination aimed at narrowing down the potential causes of the patient’s complaint. As you review the material, we encourage you to answer the questions provided to test and enhance your clinical reasoning and diagnostic skills. Additionally, consider whether all essential elements of the physical examination have been thoroughly addressed.
Vital Signs
Natalie’s vital signs are within normal limits.
Diagnostic Reasoning Question
What is the significance of normal vital signs?
ViewHide Suggested Answer
Normal vital signs typically indicate that there are no immediate life-threatening conditions. Particularly, normal temperature indicates the absence of acute infection.
Inspection
Inspection of the right preauricular area reveals no signs of swelling, redness, or deformity. An otoscopic examination of the right ear is unremarkable, with no abnormalities detected. Additionally, her head and neck posture appear normal upon inspection.
Diagnostic Reasoning Question 1
How does the lack of visible swelling, redness, or deformity in the preauricular area guide the diagnostic process?
ViewHide Suggested Answer
The absence of swelling, redness, or deformity in the preauricular area helps to rule out local inflammation, infection, or bone pathology.
Diagnostic Reasoning Question 2
How do normal findings from an ear inspection and otoscopic examination impact the diagnostic process?
ViewHide Suggested Answer
A normal ear examination helps to rule out conditions such as otitis media and otitis externa.
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Range of Motion
The TMJ active movement assessment reveals a reduced jaw opening of only 25 mm, with noticeable deviation to the right, accompanied by pain in the right TMJ. Lateral jaw movement is also limited, particularly to the left, which similarly provokes pain in the right TMJ. In contrast, both active and passive cervical range of motion assessments are found to be normal.
Diagnostic Reasoning Question
What do the findings from the TMJ active movement assessment suggest?
ViewHide Suggested Answer
The findings suggest TMJ dysfunction, potentially caused by:
- Hypertonicity or imbalance in the muscles of mastication
- Displacement of the TMJ meniscus, interfering with the normal forward movement of the mandibular condyle
- TMJ pathology, such as arthritis or local osseous issues
The normal cervical range of motion assessment helps to rule out cervical spine involvement.
If you’d like to see how the TMJ active movement assessment is performed, please watch the video below.
The resisted jaw movement assessment reveals an increase in the patient’s pain during resisted jaw closure and when resisting jaw deviation to the left.
Diagnostic Reasoning Question
How do the findings from the resisted jaw movement assessment contribute to the diagnostic process?
ViewHide Suggested Answer
These findings provide further evidence of TMJ dysfunction, potentially caused by an intra-articular disorder or involvement of the muscles of mastication.
If you would like to see how the resisted jaw movement assessment is performed, please watch the video below.
Palpation
Palpation of the right TMJ reveals tenderness, with jaw opening and closing producing a clicking sensation accompanied by pain. Additionally, the right mandibular condyle is observed to have inadequate forward sliding. Muscle palpation indicates tenderness in the right medial and lateral pterygoid, temporalis, and masseter muscles. No nodules or pain referral to the TMJ are detected on palpation of the masseter or SCM muscles. The right ear, mastoid process, and parotid gland are non-tender on palpation. A functional examination of the cervical vertebral motion segments is normal.
Diagnostic Reasoning Question 1
How do the palpation findings of tenderness in the right TMJ, pain with a clicking sensation during jaw movement, and insufficient forward sliding of the right mandibular condyle collectively inform the diagnostic process?
ViewHide Suggested Answer
The TMJ tenderness, clicking sensation, and inadequate forward movement of the right mandibular condyle strongly support a diagnosis of TMJ dysfunction.
Diagnostic Reasoning Question 2
How do the palpation findings of tenderness in the right pterygoid, temporalis, and masseter muscles, combined with the absence of nodules and pain referral in the masseter and SCM, contribute to the diagnostic process?
ViewHide Suggested Answer
The tenderness on palpation of the masticatory muscles supports the presence of TMJ dysfunction. The absence of nodules and pain referral to the TMJ upon palpation of the masseter and SCM helps to rule out myofascial pain syndrome involving these muscles.
If you would like to see how a palpation examination of the TMJ and the muscles of mastication is performed, please watch the video below.
Neurological Examination
A cranial nerve examination reveals no abnormalities, with no sensory disturbances detected in the trigeminal nerve distribution.
Diagnostic Reasoning Question
How does the absence of sensory disturbances in the trigeminal nerve distribution enhance your understanding of the patient’s jaw pain?
ViewHide Suggested Answer
The absence of sensory disturbances within the trigeminal nerve distribution indicates that the trigeminal nerve is likely not involved, further supporting TMJ dysfunction as the most probable diagnosis.
If you would like to see how a cranial nerve examination is performed, please watch the video below.
Reflection Point
Considering the patient’s history and examination findings thus far, take a moment to reflect on which special tests would be most appropriate to further evaluate this patient.
Special Tests
The Weber and Rinne tests are performed and are found to be normal.
Diagnostic Reasoning Question
What do normal Weber and Rinne test results indicate in this patient?
ViewHide Suggested Answer
Normal findings for the Weber and Rinne tests suggest no significant conductive or sensorineural hearing loss, which helps to rule out ear pathology as a contributing factor to the patient’s symptoms. This further directs the focus towards TMJ dysfunction or other non-auditory causes of jaw pain and associated symptoms.
To see how these tests are performed, please watch the videos below.
The Axial Cervical Compression test yields a negative result, with no localized upper neck pain or referral to the preauricular region.
Diagnostic Reasoning Question
What does a negative result for this test indicate in a patient with jaw pain?
ViewHide Suggested Answer
The Axial Cervical Compression test is primarily used to assess for nerve root involvement in the cervical spine. Although it’s not directly related to evaluating jaw pain, it can offer valuable insights in cases where cervical spine pathology might contribute to or mimic jaw pain. Involvement of the cervical facet joints, particularly the C1-C2 facet joints, can lead to localized neck pain or referred pain to the skull. As shown below, specifically, these joints may cause pain referral to the preauricular, occipital, and orbital regions, as well as the vertex. The negative result of this patient’s Axial Cervical Compression test suggests that the upper cervical facet joints are not involved.

Reflection Point
Please pause and assess whether all the essential elements of a thorough and relevant physical examination have been completed for this patient. Are there any additional procedures you would have performed? If so, why?
Diagnosis
Diagnostic Reasoning Question
Based on the available information, what is the most likely diagnosis?
ViewHide Suggested Answer
Right TMJ dysfunction.
References and Suggested Further Readings
Pavia S. et al. Chiropractic Treatment of Temporomandibular Dysfunction: A Retrospective Case Series. J Chiropr Med. 2015 Dec;14(4):279-84.
Lomas J. et al. Temporomandibular dysfunction. AJGP. Volume 47, Issue 4, April 2018.
Travell J. Temporomandibular joint pain referred from muscles of the head and neck. J Pros Dent. 1960;10:745.
Shanavas M. et al. Transcutaneous electrical nerve stimulation therapy: An adjuvant pain controlling modality in TMD patients – A clinical study. Dent Res J (Isfahan). 2014 Nov;11(6):676-9.
Ba S. et al. Ultrasound is Effective to Treat Temporomandibular Joint Disorder. J Pain Res. 2021 Jun 10;14:1667-1673.
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Disclaimer: The acemsk.com website (including text, graphics, downloadable resources, and videos) is intended to provide general health information for educational purposes only. This information is not a substitute for personal consultation with a qualified healthcare professional. Always seek the advice of a healthcare professional for any questions regarding your condition, symptoms, and appropriate treatments.
Copyright © Educom Pty Ltd: All content on the acemsk.com website, including text, graphics, videos, and downloadable files, is the property of Educom Continuing Education, a division of Educom Pty Ltd, and is protected by copyright and other intellectual property laws under international conventions. Unauthorized use or duplication of this material without express written permission from Educom Pty Ltd is strictly prohibited.

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